Chandipura Virus

Read about the oldest known Chandipura Virus which was first isolated in 1965 in Nagpur, Maharashtra.

About the Virus

The virus is a member of the Vesiculovirus genus of the family Rhabdoviridae. Incidentally this family also includes the rabies virus.
First isolated in 1965 in a village in Nagpur, Maharashtra. The virus is reportedly named after the village it was isolated from.
The virus is vector-borne, with the likely vector believed to be the female Phlebotomine sandfly, insects that are prevalent in the early monsoon period.
- Several species of mosquitoes replicated and transmitted the virus experimentally, and among the different mosquito species.
- Aedes aegypti, (which also transmits dengue), was found to be highly susceptible and could transmit the virus more efficiently than others, under laboratory conditions.
There is no specific antiviral agent to treat Chandipura virus and there is no vaccine available as of yet. Early diagnosis and treatment are key.

rapid onset of fever
the fever is followed by vomiting
altered sensorium (a change in mental status or consciousness)
convulsions, diarrhoea
neurological deficit (examples include an inability to speak, loss of balance, vision changes)
meningeal irritation (signs may include headaches, neck stiffness, photophobia and seizures).

Vector control –
- identifying sandfly breeding sites,
- spraying insecticides,
- sanitation,
Environmental control –
- proper storage and disposal of waste and refuse,
- stopping open air defecation,
- and the use of fly paper.
Breeding sites –
- holes and crevices in walls,
- holes in trees, dark rooms, stables and storerooms.
Use of protective clothing, repellants and nets.